Reaction of epoxied with amine catalyzed by Lewis acid.
نویسندگان
چکیده
منابع مشابه
A mild procedure for the Lewis acid-catalyzed ring-opening of activated cyclopropanes with amine nucleophiles.
The Lewis acid-catalyzed ring-opening of methyl 1-nitrocyclopropanecarboxylates with amine nucleophiles is described. The reaction proceeds at room temperature and with complete preservation of the enantiomeric purity from the electrophilic center of the cyclopropane to the acyclic product. The methodology was applied in an enantioselective synthesis of the dual serotonin/norepinephrine reuptak...
متن کاملLewis Acid and/or Lewis Base catalyzed [3+2] cycloaddition reaction: Synthesis of pyrazoles and pyrazolines
Abstract: A facile, 1,3-dipolar cycloaddition of ethyl diazoacetate (EDA) with various activated olefins including Baylis-Hillman adducts, activated and simple alkynes to afford 3,5-disubstituted pyrazolines and pyrazoles respectively in moderate to good yields, in high regioselective manner in the presence of Indium chloride and/or DABCO is reported. All the reactions were carried out under no...
متن کاملIron-catalyzed amination of alcohols assisted by Lewis acid.
An efficient Lewis acid-assisted, iron-catalyzed amination of alcohols using borrowing hydrogen methodology was developed. In particular, silver fluoride was identified to be a highly effective additive to overcome the low efficiency in the amination of secondary alcohols catalyzed by Knölker's complex.
متن کاملMetalloenzyme-like catalyzed isomerizations of sugars by Lewis acid zeolites.
Isomerization of sugars is used in a variety of industrially relevant processes and in glycolysis. Here, we show that hydrophobic zeolite beta with framework tin or titanium Lewis acid centers isomerizes sugars, e.g., glucose, via reaction pathways that are analogous to those of metalloenzymes. Specifically, experimental and theoretical investigations reveal that glucose partitions into the zeo...
متن کاملDevelopment of fluorous Lewis acid-catalyzed reactions.
Organic synthetic methodology in the 21st century aims to conform to the principles of green sustainable chemistry (GSC) and we may expect that in the future, the realization of GSC will be an important objective for chemical industries. An important aim of synthetic organic chemistry is to implement waste-free and environmentally-benign industrial processes using Lewis acids as versatile as al...
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ژورنال
عنوان ژورنال: Journal of Advanced Science
سال: 1993
ISSN: 1881-3917,0915-5651
DOI: 10.2978/jsas.5.4_115